Compartmentalized Ras signaling differentially contributes to phenotypic outputs
نویسندگان
چکیده
منابع مشابه
Compartmentalized Ras signaling differentially contributes to phenotypic outputs☆
Ras isoforms are membrane bound proteins that differentially localize to the plasma membrane and subcellular compartments within the cell. Whilst the cell surface is the main site for Ras activity the extent to which intracellular pools contribute to Ras function is debated. We have generated Ras chimeras targeting Ras to the ER, Golgi, mitochondria and endosomes to compare the capacity of each...
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ژورنال
عنوان ژورنال: Cellular Signalling
سال: 2013
ISSN: 0898-6568
DOI: 10.1016/j.cellsig.2013.05.004